4-Cyano-3-(trifluoromethyl)aniline
aniline.svg.png) | |
| Names | |
|---|---|
| IUPAC name
4-Amino-2-(trifluoromethyl)benzonitrile | |
| Other names
4-Cyano-3-(trifluoromethyl)aniline | |
| Identifiers | |
| 654-70-6 | |
| 3D model (Jmol) | Interactive image |
| ChemSpider | 455494 |
| PubChem | 522170 |
| UNII | L47D9XHC08 |
| |
| Properties | |
| C8H5F3N2 | |
| Molar mass | 186.14 g·mol−1 |
| Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
| Infobox references | |
4-Cyano-3-(trifluoromethyl)aniline, also known as 4-amino-2-(trifluoromethyl)benzonitrile, is a cyanated and trifluoromethylated derivative of aniline. It is the starting material in one of the chemical syntheses of the non-steroidal antiandrogen bicalutamide.[1]
References
- ↑ Tucker H, Crook JW, Chesterson GJ (1988). "Nonsteroidal antiandrogens. Synthesis and structure-activity relationships of 3-substituted derivatives of 2-hydroxypropionanilides". Journal of Medicinal Chemistry. 31 (5): 954–9. doi:10.1021/jm00400a011. PMID 3361581.
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