Aurotioprol

Aurotioprol
Clinical data

AHFS/Drugs.com	International Drug Names
Routes of administration	Intramuscular injection
ATC code	M01CB05 (WHO)
Identifiers
IUPAC name Sodium aurothiopropanolsulfonate
PubChem (CID)	44144564
ChemSpider	8628381
UNII	G7097J63E9^Y
Chemical and physical data
Formula	C₃H₆AuNaO₄S₂
Molar mass	390.16
3D model (Jmol)	Interactive image
SMILES C(C(CS(=O)(=O)[O-])O)[S-].[Na+].[Au+]
InChI InChI=1S/C3H8O4S2.Au.Na/c4-3(1-8)2-9(5,6)7;;/h3-4,8H,1-2H2,(H,5,6,7);;/q;2*+1/p-2 Key:KBWWFTIQBJUOQR-UHFFFAOYSA-L
(verify)

Aurotioprol is a gold salt used as an antirheumatic agent.^[1]^[2]

References

↑ Perrier, P.; Raffoux, C.; Thomas, P.; Tamisier, J. N.; Busson, M.; Gaucher, A.; Streiff, F. (1985). "HLA antigens and toxic reactions to sodium aurothiopropanol sulphonate and D-penicillamine in patients with rheumatoid arthritis". Annals of the rheumatic diseases. 44 (9): 621–624. doi:10.1136/ard.44.9.621. PMC 1001721. PMID 3876081.
↑ Veys, E. M.; Mielants, H.; Verbruggen, G. (1987). "Goldsalts, levamisole and D-penicillamine as first choice slow-acting antirheumatic drugs in rheumatoid arthritis--a long-term follow-up study". Clinical and experimental rheumatology. 5 (2): 111–116. PMID 3608266.

Specific antirheumatic products / DMARDs (M01C)

Quinolines	Oxycinchophen

Gold preparations	Sodium aurothiomalate Sodium aurothiosulfate Auranofin Aurothioglucose Aurotioprol

Other	Penicillamine #/Bucillamine Chloroquine #/Hydroxychloroquine Leflunomide Sulfasalazine # antifolate (Methotrexate #) thiopurine (Azathioprine) #

^#WHO-EM ^‡Withdrawn from market Clinical trials: ^†Phase III ^§Never to phase III

Gold compounds

Gold(-I)

Gold(I)

Organogold(I) compounds	(AuC₆H₂(CH₃)₃)₅

Gold(II)

Gold(I,III)

Gold(III)

Gold(V)

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