Ciclobendazole

Ciclobendazole
Clinical data

ATC code	P02CA04 (WHO)
Identifiers
IUPAC name Methyl N-[6-(cyclopropanecarbonyl)-1H-benzimidazol-2-yl]carbamate
CAS Number	31431-43-3^Y
PubChem (CID)	35803
ChemSpider	32933^N
UNII	JF3KQ40J31^Y
KEGG	D03623^Y
ECHA InfoCard	100.046.018
Chemical and physical data
Formula	C₁₃H₁₃N₃O₃
Molar mass	259.26 g/mol
3D model (Jmol)	Interactive image
SMILES O=C(c2cc1c(nc(n1)NC(=O)OC)cc2)C3CC3
InChI InChI=1S/C13H13N3O3/c1-19-13(18)16-12-14-9-5-4-8(6-10(9)15-12)11(17)7-2-3-7/h4-7H,2-3H2,1H3,(H2,14,15,16,18)^N Key:OXLKOMYHDYVIDM-UHFFFAOYSA-N^N
^NY (what is this?) (verify)

Ciclobendazole is an anthelmintic.

Antiparasitics – Anthelmintics (P02) and Endectocides (QP54)

Antiplatyhelmintic agents

Antitrematodals
(schistosomicides)

Binds tubulin	benzimidazole Triclabendazole^#

AI	phosphonic acid Metrifonate^‡

Other/unknown	quinoline Praziquantel^# Oxamniquine^# phenol Bithionol thiazole Niridazole arylsulfonate Stibophen

Anticestodals
(taeniacides)

Binds tubulin	benzimidazole Albendazole^#

Other/unknown	quinoline Praziquantel^# salicylanilide Niclosamide^# aminoacridine Quinacrine butyrophenone Desaspidin chlorophenol Dichlorophen

Antinematodal agents
(including
macrofilaricides)

Binds tubulin	benzimidazole Mebendazole^# Albendazole^# Tiabendazole Fenbendazole Ciclobendazole Flubendazole

Glutamate-gated chloride channel, GABA receptor	avermectins Abamectin Doramectin Emamectin Ivermectin^# Selamectin milbemycins Moxidectin Milbemycin oxime

NMDA	tetrahydropyrimidine Pyrantel^# pyrantel pamoate Oxantel Morantel Carbantel Febantel (aka felsantel)

Other/unknown	piperazine Piperazine Diethylcarbamazine^# thiazole Levamisole^# quinolinium Pyrvinium benzylammonium Bephenium naphthalenesulfonate Suramin^# Tribendimidine

^#WHO-EM
^‡Withdrawn from market
Clinical trials:
- ^†Phase III
- ^§Never to phase III

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