Dextromethadone
 | |
| Names | |
|---|---|
| IUPAC name
(6S)-6-(Dimethylamino)-4,4-diphenylheptan-3-one | |
| Other names
d-Methadone; 6S-Methadone; (+)-Methadone | |
| Identifiers | |
| 5653-80-5 | |
| 3D model (Jmol) | Interactive image |
| ChemSpider | 559067 |
| ECHA InfoCard | 100.164.915 |
| PubChem | 643985 |
| |
| |
| Properties | |
| C21H27NO | |
| Molar mass | 309.45 g·mol−1 |
| Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
| Infobox references | |
Dextromethadone is an antitussive opioid.[1] It is the (S)-enantiomer of methadone.
There is now an asymmetric synthesis[2] available to prepare both dextromethadone [S-(+)-methadone] and levomethadone [R-(−)-methadone].[3]
See also
References
- ↑ Rasch, M (1957). "Dextromethadone and its antitussive effect". Nordisk medicin. 57 (17): 629–31. PMID 13441112.
- ↑ Hull JD, Scheinmann F, Turner NJ (March 2003). "Synthesis of optically active methadones, LAAM and bufuralol by lipase-catalysed acylations". Tetrahedron: Asymmetry. 14 (5): 567–576. doi:10.1016/S0957-4166(03)00019-3.
- ↑ US patent 6143933
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