EGOT (gene)
| EGOT | ||||||
|---|---|---|---|---|---|---|
| Identifiers | ||||||
| Aliases | EGOT, EGO, NCRNA00190, eosinophil granule ontogeny transcript (non-protein coding) | |||||
| External IDs | GeneCards: EGOT | |||||
| Orthologs | ||||||
| Species | Human | Mouse | ||||
| Entrez |
| |||||
| Ensembl |
| |||||
| UniProt |
|
| ||||
| RefSeq (mRNA) |
|
| ||||
| RefSeq (protein) |
|
| ||||
| Location (UCSC) | Chr 3: 4.75 – 4.75 Mb | n/a | ||||
| PubMed search | [1] | n/a | ||||
| Wikidata | ||||||
| View/Edit Human | |||
EGOT, also known as Eosinophil Granule Ontogeny (EGO)† Transcript (non-protein coding),[2] is a human gene at 3p26.1 that produces a long noncoding RNA molecule. EGOT is nested within an intron of the inositol triphosphate receptor type 1 (ITPR1) gene. The EGOT transcript is expressed during eosinophil development and is possibly involved in regulating eosinophil granule protein expression.[2] Comparison of EGO-B, the spliced isoform, suggests EGOT may be conserved across placental mammals.[3]
†Originally published as EGO but renamed as EGOT because 'EGO' is a real word and is therefore problematic when searching the scientific literature.[4]
References
- ↑ "Human PubMed Reference:".
- 1 2 Wagner LA, Christensen CJ, Dunn DM, et al. (June 2007). "EGO, a novel, noncoding RNA gene, regulates eosinophil granule protein transcript expression". Blood. 109 (12): 5191–8. doi:10.1182/blood-2006-06-027987. PMC 1890841
. PMID 17351112. - ↑ Rose D, Stadler PF (October 2011). "Molecular evolution of the non-coding eosinophil granule ontogeny transcript". Front Genet. 2. doi:10.3389/fgene.2011.00069. PMC 3268622. PMID 22303364.
- ↑ Wright, MW (Apr 9, 2014). "A short guide to long non-coding RNA gene nomenclature.". Human genomics. 8: 7. doi:10.1186/1479-7364-8-7. PMC 4021045. PMID 24716852.
This article is issued from Wikipedia - version of the 6/17/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.