Fenoxazoline

Fenoxazoline
Clinical data

Trade names	Aturgyl, Nasofelin, Nebulicina
AHFS/Drugs.com	International Drug Names
Routes of administration	Topical (nasal solution)
ATC code	R01AA12 (WHO)
Legal status
Legal status	℞-only (BR)
Identifiers
IUPAC name 2-[(2-propan-2-ylphenoxy)methyl]-4,5-dihydro-1H-imidazole
CAS Number	4846-91-7^Y
PubChem (CID)	71899
ChemSpider	64911^N
UNII	97JJW1W1R3^Y
KEGG	D07372^Y
ChEMBL	CHEMBL14012^N
ECHA InfoCard	100.023.124
Chemical and physical data
Formula	C₁₃H₁₈N₂O
Molar mass	218.295 g/mol
3D model (Jmol)	Interactive image
SMILES CC(C)C1=CC=CC=C1OCC2=NCCN2
InChI InChI=1S/C13H18N2O/c1-10(2)11-5-3-4-6-12(11)16-9-13-14-7-8-15-13/h3-6,10H,7-9H2,1-2H3,(H,14,15)^N Key:GFYSWQDCHLWRMQ-UHFFFAOYSA-N^N
^NY (what is this?) (verify)

Fenoxazoline (trade name Aturgyl in Brazil) is a nasal decongestant.^[1]

Fenmetozole has the precise same formula, albeit instead of an ortho-isopropyl group, 3',4'-dich was chosen instead.

References

↑ Lorino, A. M.; Lofaso, F.; Dahan, E.; Coste, A.; Harf, A.; Lorino, H. (1999). "Combined effects of a mechanical nasal dilator and a topical decongestant on nasal airflow resistance". Chest. 115 (6): 1514–1518. doi:10.1378/chest.115.6.1514. PMID 10378542.

Decongestants and other nasal preparations (R01)

Sympathomimetics, plain	Cyclopentamine Ephedrine Epinephrine Fenoxazoline Levomethamphetamine Metizoline Naphazoline Oxymetazoline Phenylephrine Propylhexedrine Tetryzoline Tramazoline Tuaminoheptane Tymazoline Xylometazoline

Antiallergic agents, excluding corticosteroids	Spaglumic acid histamine antagonists (Levocabastine Antazoline Thonzylamine) mast cell stabilizer (some are also antihistamines) (Cromoglicic acid Nedocromil Azelastine Olopatadine Lodoxamide)

Corticosteroids	Beclometasone dipropionate Betamethasone Budesonide Ciclesonide Dexamethasone Flunisolide Fluticasone Mometasone furoate Prednisolone Tixocortol Triamcinolone

Other nasal preparations	Cafaminol Calcium hexamine thiocyanate Eucalyptus oil Framycetin Hexamidine Hyaluronan Ipratropium bromide Mupirocin Retinol Ritiometan Saline water

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