Hymecromone

Hymecromone
Clinical data

AHFS/Drugs.com	International Drug Names
ATC code	A05AX02 (WHO)
Identifiers
IUPAC name 7-Hydroxy-4-methylchromen-2-one
Synonyms	4-Methylumbelliferone
CAS Number	90-33-5^Y
PubChem (CID)	5280567
DrugBank	DB07118^Y
ChemSpider	4444190^Y
UNII	3T5NG4Q468^Y
KEGG	D00170^Y
ChEBI	CHEBI:17224^Y
ChEMBL	CHEMBL12208^Y
ECHA InfoCard	100.001.806
Chemical and physical data
Formula	C₁₀H₈O₃
Molar mass	176.17 g/mol
3D model (Jmol)	Interactive image
SMILES O=C/2Oc1cc(O)ccc1\C(=C\2)C
InChI InChI=1S/C10H8O3/c1-6-4-10(12)13-9-5-7(11)2-3-8(6)9/h2-5,11H,1H3^Y Key:HSHNITRMYYLLCV-UHFFFAOYSA-N^Y
(verify)

Hymecromone (4-methylumbelliferone) is a drug used in bile therapy. It is used as choleretic and antispasmodic drugs and as a standard for the fluorometric determination of enzyme activity.

Hymecromone is a crystalline solid with a melting point of 194–195 °C. It is soluble in methanol and glacial acetic acid.

Bile and liver therapy (A05)

Bile therapy	bile acid (Chenodeoxycholic acid Cholic acid Ursodeoxycholic acid) Obeticholic acid Nicotinyl methylamide Piprozolin Hymecromone Cyclobutyrol

Liver therapy	Arginine glutamate Silymarin Citiolone Epomediol Ornithine oxoglutarate Tidiacic arginine Glycyrrhizin

Types of coumarins

Aglycones

O-Methylated	Fraxetin Herniarin (7-O-Methylumbelliferone) Osthol Scopoletin (6-Methoxyumbelliferone)

glycosides

Aesculin (Esculetin 6-O-glucoside)
Fraxin (Fraxetin glucoside)
Skimmin (Umbelliferone 7-O-glucoside)
Scopolin
Umbelliferone 7-apiosylglucoside

derivatives

Furanocoumarins

Aglycones

Angelicin
Marmesin
Psoralen
Vaginol
Xanthotoxol (8-Hydroxypsoralen)

O-Methylated	Bergapten (5-methoxypsoralen) Isopimpinellin (5,8-Dimethoxypsoralene) Methoxsalen (8-Methoxypsoralen) Trioxsalen (2,5,9-Trimethylpsoralen)

Furanocoumarin glycosides

Apterin (vaginol glucoside)

Meroterpene furanocoumarin ether

Oligomers

Dicoumarol

Synthetic

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Hymecromone

See also