Isoaminile

Isoaminile
Clinical data

AHFS/Drugs.com	International Drug Names
ATC code	R05DB04 (WHO)
Identifiers
IUPAC name 4-(dimethylamino)-2-isopropyl-2-phenylpentanenitrile
CAS Number	77-51-0^Y
PubChem (CID)	6481
DrugBank	DB08944^N
ChemSpider	6236^Y
UNII	R4823W2PQL^Y
KEGG	D08088^Y
ECHA InfoCard	100.000.940
Chemical and physical data
Formula	C₁₆H₂₄N₂
Molar mass	244.375 g/mol
3D model (Jmol)	Interactive image
SMILES N#CC(c1ccccc1)(C(C)C)CC(N(C)C)C
InChI InChI=1S/C16H24N2/c1-13(2)16(12-17,11-14(3)18(4)5)15-9-7-6-8-10-15/h6-10,13-14H,11H2,1-5H3^Y Key:WFLSCFISQHLEED-UHFFFAOYSA-N^Y
^NY (what is this?) (verify)

Isoaminile is an antitussive (cough suppressant) used under the trade-name Peracon.^[1]

The normal therapeutic dose is 40–80 mg of the cyclamate salt, with a maximum of five doses in a 24-hour period. In addition to its central antitussive effects, it is also an anticholinergic, exhibiting both antimuscarinic and antinicotinic actions.

References

↑ Chappel, C. I.; von Seeman, C. (1963). "Antitussive Drugs". In Ellis, G. P.; West, G. B. Progress in Medicinal Chemistry. 3. Butterworth. pp. 114–115. doi:10.1016/S0079-6468(08)70117-6. ISBN 978-0-444-53322-7. Retrieved 2013-09-12.

Cough and cold preparations (R05)

Expectorants

Mucolytics

Cough suppressants

Opium alkaloids, opioids, and derivatives	Acetyldihydrocodeine Benzylmorphine Butorphanol Codeine Dextromethorphan Dihydrocodeine Dimemorfan Droxypropine Ethylmorphine Heroin Hydrocodone Hydromorphone Isoaminile Laudanum Levomethadone Levopropoxyphene Methadone Nicocodeine Nicodicodeine Normethadone Noscapine Pholcodine Thebacon Tipepidine

Other	Benzonatate Benproperine Bibenzonium bromide Butamirate Clobutinol Clofedanol Cloperastine Diphenhydramine Dibunate Dimethoxanate Dropropizine Fedrilate Glaucine Levodropropizine Meprotixol Morclofone Nepinalone Oxolamine Oxeladin Pentoxyverine Pipazetate Prenoxdiazine Piperidione Zipeprol

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