Propamidine

Propamidine
Names


IUPAC name 4,4'-[propane-1,3-diylbis(oxy)]dibenzenecarboximidamide
Identifiers
CAS Number	104-32-5^N 140-63-6 (isethionate)^N
3D model (Jmol)	Interactive image
ChEBI	CHEBI:87462^N
ChEMBL	ChEMBL23013^Y
ChemSpider	58475^Y
ECHA InfoCard	100.002.905
PubChem	64949
UNII	G20G12V769^Y
InChI InChI=1S/C17H20N4O2/c18-16(19)12-2-6-14(7-3-12)22-10-1-11-23-15-8-4-13(5-9-15)17(20)21/h2-9H,1,10-11H2,(H3,18,19)(H3,20,21)^Y Key: WTFXJFJYEJZMFO-UHFFFAOYSA-N^Y InChI=1/C17H20N4O2/c18-16(19)12-2-6-14(7-3-12)22-10-1-11-23-15-8-4-13(5-9-15)17(20)21/h2-9H,1,10-11H2,(H3,18,19)(H3,20,21) Key: WTFXJFJYEJZMFO-UHFFFAOYAO
SMILES O(c1ccc(cc1)C(=[N@H])N)CCCOc2ccc(C(=[N@H])N)cc2
Properties
Chemical formula	C₁₇H₂₀N₄O₂
Molar mass	312.37 g/mol
Pharmacology
ATC code	D08AC03 (WHO) S01AX15 (WHO)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is ^YN ?)
Infobox references

Propamidine is an antiseptic and disinfectant.

Propamidine isethionate, the salt of propamidine with isethionic acid, is used in the treatment of Acanthamoeba infection.^[1]

References

↑ Perrine D, Chenu JP, Georges P, Lancelot JC, Saturnino C, Robba M (February 1995). "Amoebicidal efficiencies of various diamidines against two strains of Acanthamoeba polyphaga". Antimicrob. Agents Chemother. 39 (2): 339–42. doi:10.1128/aac.39.2.339. PMC 162538. PMID 7726493.

Antiseptics and disinfectants (D08)

Acridine derivatives	Ethacridine lactate 9-Aminoacridine Euflavine

Biguanides and amidines	Dibrompropamidine Chlorhexidine^# Propamidine Hexamidine Polihexanide

Phenol and derivatives	Hexachlorophene Policresulen Phenol Triclosan Triclocarban Chloroxylenol^# Biphenylol Fenticlor

Nitrofuran derivatives	Nitrofurazone

Iodine products	Iodine/octylphenoxypolyglycolether Povidone-iodine^# Diiodohydroxypropane

Quinoline derivatives	Dequalinium Chlorquinaldol Oxyquinoline Clioquinol

Quaternary ammonium compounds	Benzalkonium Benzethonium chloride Cetrimonium (bromide/chloride) Cetylpyridinium Cetrimide Benzoxonium chloride Didecyldimethylammonium chloride

Mercurial products	Mercuric amidochloride Phenylmercuric borate Mercuric chloride Merbromin Thiomersal Mercuric iodide

Silver compounds	Silver nitrate

Alcohols	Propanol (propyl alcohol) Isopropanol (isopropyl alcohol) Ethanol (ethyl alcohol)^#

Other	Potassium permanganate Sodium hypochlorite Hydrogen peroxide Eosin Tosylchloramide Octenidine dihydrochloride

^#WHO-EM ^‡Withdrawn from market Clinical trials: ^†Phase III ^§Never to phase III

Nitroimidazole derivatives	Metronidazole^# Tinidazole Ornidazole Nimorazole Secnidazole Azanidazole Propenidazole

Other	isoquinoline (Emetine/Dehydroemetine)

Hydroxyquinoline derivatives	Cl (Chlorquinaldol) Br (Tilbroquinol Broxyquinoline) I (Diiodohydroxyquinoline) I, Cl (Clioquinol) related: Chiniofon

Dichloroacetamide derivatives	Diloxanide^# Clefamide Etofamide Teclozan

Aminoglycoside	Paromomycin

Other/ungrouped

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