Trengestone
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| Clinical data | |
|---|---|
| Routes of administration | Oral |
| ATC code | None |
| Legal status | |
| Legal status |
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| Identifiers | |
| |
| Synonyms | Ro 4-8347; 1,6-bisdehydro-6-chlororetroprogesterone[1] |
| CAS Number | 5192-84-7 |
| PubChem (CID) | 56840930 |
| ChemSpider | 16736068 |
| Chemical and physical data | |
| Formula | C21H25ClO2 |
| Molar mass | 344.875 g/mol |
| 3D model (Jmol) | Interactive image |
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Trengestone (INN) (brand names Reteroid, Retroid, Retrone; former developmental code name Ro 4-8347), also known as 6-chloro-6,7-didehydroretroprogesterone or 6-chloro-9β-10α-pregna-1,4,6-triene-3,20-dione, is a steroidal progestin of the retroprogesterone group[2] related to dydrogesterone that was formerly used to treat menstrual disorders.[3][4][5] It was synthesized in 1964 and was introduced for medical use by Roche in 1974.[3][4][5]
References
- ↑ Andreoli C, Fiorentino F, Lenzi G (September 1970). "[Clinical studies and endometrial histomorphological findings by means of a new retroprogesterone derivative: 1,6 bis dehydro-6-chloro-retroprogesterone (Trengestone)]". Minerva Ginecol (in Italian). 22 (18): 874–9. PMID 4925556.
- ↑ J. Horsky; J. Presl (6 December 2012). Ovarian Function and its Disorders: Diagnosis and Therapy. Springer Science & Business Media. pp. 329–. ISBN 978-94-009-8195-9.
- 1 2 J. Elks (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 259–. ISBN 978-1-4757-2085-3.
- 1 2 Pascale Brudon (1983). Médicaments pour tous en l'an 2000?: les multinationales pharmaceutiques suisses face au tiers monde : l'exemple du Mexique. Editions d'en bas. pp. 93–. ISBN 978-2-8290-0039-3.
- 1 2 Dr. Ian Morton; I.K. Morton; Judith M. Hall (31 October 1999). Concise Dictionary of Pharmacological Agents: Properties and Synonyms. Springer Science & Business Media. pp. 279–. ISBN 978-0-7514-0499-9.
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