Urtoxazumab
| Monoclonal antibody | |
|---|---|
| Type | Whole antibody |
| Source | Humanized (from mouse) |
| Target | E. coli Shiga-like toxin II B subunit |
| Clinical data | |
| ATC code | none |
| Identifiers | |
| CAS Number |
502496-16-4  |
| ChemSpider | none |
| Chemical and physical data | |
| Formula | C6414H9934N1718O2010S40 |
| Molar mass | 144.6 kg/mol |
 (what is this?) (verify) | |
Urtoxazumab is a humanized monoclonal antibody against diarrhoea caused by Escherichia coli, serotype O121. The drug is designed to bind to a toxin of this bacterium, so that it can be more easily broken down and eliminated from the body.[1][2]
References
- ↑ International Nonproprietary Names for Pharmaceutical Substances (INN), World Health Organization.
- ↑ López, EL; Contrini, MM; Glatstein, E; González Ayala, S; Santoro, R; Allende, D; Ezcurra, G; Teplitz, E; et al. (2009). "Safety and Pharmacokinetics of Urtoxazumab, a Humanized Monoclonal Antibody Against Shiga-Like Toxin 2 in Healthy Adults and Pediatric STEC- Infected Patients". Antimicrobial Agents and Chemotherapy. 54 (1): 239–243. doi:10.1128/AAC.00343-09. PMC 2798559
. PMID 19822704.
This article is issued from Wikipedia - version of the 10/9/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.