Magnesium pyridoxal 5-phosphate glutamate

Magnesium pyridoxal 5-phosphate glutamate
Clinical data

Trade names	Sedalipid
ATC code	C10AX07 (WHO)
Identifiers
IUPAC name (2S)-2,5-diamino-5-oxopentanoic acid; (4-formyl-5-hydroxy-6-methylpyridin-3-yl)methyl dihydrogen phosphate
CAS Number	62055-05-4 (magnesium salt)
PubChem (CID)	173846
ChemSpider	151728^Y
Chemical and physical data
Formula	C₁₃H₂₀N₃O₉P
Molar mass	393.286 g/mol
3D model (Jmol)	Interactive image
SMILES O=C(N)CC[C@H](N)C(=O)O.O=P(O)(O)OCc1cnc(c(O)c1C=O)C
InChI InChI=1S/C8H10NO6P.C5H10N2O3/c1-5-8(11)7(3-10)6(2-9-5)4-15-16(12,13)14;6-3(5(9)10)1-2-4(7)8/h2-3,11H,4H2,1H3,(H2,12,13,14);3H,1-2,6H2,(H2,7,8)(H,9,10)/t;3-/m.0/s1^Y Key:BCARVEADLDZBJT-HVDRVSQOSA-N^Y
(verify)

Magnesium pyridoxal 5-phosphate glutamate (trade name Sedalipid) is a hypolipidemic agent.^[1]

References

↑ Schuitemaker GE, van der Pol GA, Aretz CP, Dinant GJ (2001). "A placebo-controlled, double-blind, randomised trial of magnesium-pyridoxal-5'-phosphate-glutamate for hypercholesterolaemia and other clinical-chemical risk factors of cardiovascular disease in a primary care setting". Eur. J. Clin. Pharmacol. 56 (12): 857–63. doi:10.1007/s002280000247. PMID 11317472.

Cholesterol absorption inhibitors, NPC1L1	Ezetimibe SCH-48461

Bile acid sequestrants/resins (LDL)	Colestyramine Colestipol Colestilan Colextran Colesevelam

Statins (HMG-CoA reductase, LDL)	Simvastatin^# Atorvastatin Fluvastatin Lovastatin Mevastatin Pitavastatin Pravastatin Rosuvastatin Cerivastatin^‡

Niacin and derivatives (HDL and LDL)	Niceritrol Niacin Nicofuranose Aluminium nicotinate Nicotinyl alcohol Acipimox

MTTP inhibitors (VLDL)	Dirlotapide Lomitapide Mitratapide

Fibrates (PPAR)	Clofibrate^‡ Bezafibrate Aluminium clofibrate Gemfibrozil Fenofibrate Simfibrate Ronifibrate Ciprofibrate Etofibrate Clofibride Clinofibrate

CETP inhibitors (HDL)	Anacetrapib^† Dalcetrapib^§ Evacetrapib^§ Torcetrapib^§

Combinations

Other

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