Picloxydine

Picloxydine
Names

IUPAC name 1-N',4-N'-bis[N'-(4-chlorophenyl)carbamimidoyl]piperazine-1,4-dicarboximidamide
Identifiers
CAS Number	5636-92-0^Y
3D model (Jmol)	Interactive image
ChEMBL	ChEMBL2104722^N
ChemSpider	64722^N
ECHA InfoCard	100.024.623
PubChem	71663
UNII	4YC2PY3AEU^Y
InChI InChI=1S/C20H24Cl2N10/c21-13-1-5-15(6-2-13)27-17(23)29-19(25)31-9-11-32(12-10-31)20(26)30-18(24)28-16-7-3-14(22)4-8-16/h1-8H,9-12H2,(H4,23,25,27,29)(H4,24,26,28,30)^N Key: YNCLPFSAZFGQCD-UHFFFAOYSA-N^N InChI=1/C20H24Cl2N10/c21-13-1-5-15(6-2-13)27-17(23)29-19(25)31-9-11-32(12-10-31)20(26)30-18(24)28-16-7-3-14(22)4-8-16/h1-8H,9-12H2,(H4,23,25,27,29)(H4,24,26,28,30) Key: YNCLPFSAZFGQCD-UHFFFAOYAM
SMILES C1CN(CCN1C(=NC(=NC2=CC=C(C=C2)Cl)N)N)C(=NC(=NC3=CC=C(C=C3)Cl)N)N
Properties
Chemical formula	C₂₀H₂₄Cl₂N₁₀
Molar mass	475.37756
Pharmacology
ATC code	S01AX16 (WHO)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is ^YN ?)
Infobox references

Picloxydine (trade name Vitabact^[1]) is a bisbiguanide antiseptic used in eye drops. It is structurally similar to chlorhexidine.

References

↑ Obikili AG, Oji EO, Shonekan RO, Otti P (1988). "A double-blind comparison of picloxydine dihydrochloride (Vitabact eye drops) and sulfacetamide eye drops in the topical therapy of trachoma". Rev Int Trach Pathol Ocul Trop Subtrop Sante Publique. 65 (3–4): 119–32. PMID 3274675.

Ophthalmologicals: anti-infectives (S01A)

Antibiotics	amphenicols (Chloramphenicol Azidamfenicol) tetracyclines (Tetracycline Chlortetracycline Oxytetracycline) aminoglycosides (Dihydrostreptomycin Neomycin Framycetin Kanamycin Amikacin Tobramycin Gentamicin Netilmicin Micronomicin) macrolides (Erythromycin Natamycin) beta-lactams (Ampicillin Benzylpenicillin) polypeptides (Polymyxin B Tyrothricin) Rifamycin Fusidic acid

Sulfonamides	Sulfamethizole Sulfafurazole Sulfadicramide Sulfacetamide Sulfafenazol

Antivirals	Idoxuridine Trifluridine Aciclovir Interferon Vidarabine Famciclovir Fomivirsen Ganciclovir

Other	Nitrofural Bibrocathol Resorcinol Sodium borate Hexamidine Chlorhexidine Sodium propionate Ofloxacin Norfloxacin Ciprofloxacin Dibrompropamidine Propamidine Picloxydine Lomefloxacin Povidone-iodine Levofloxacin Gatifloxacin

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