Chlormidazole

Not to be confused with Clomethiazole or Clotrimazole.

Chlormidazole
Clinical data

AHFS/Drugs.com	International Drug Names
ATC code	D01AC04 (WHO)
Identifiers
IUPAC name 1-[(4-chlorophenyl)methyl]-2-methylbenzimidazole
CAS Number	3689-76-7
PubChem (CID)	71821
ChemSpider	64845
UNII	8IKK64FJVX^Y
KEGG	D02557
ChEMBL	CHEMBL152649
ECHA InfoCard	100.020.908
Chemical and physical data
Formula	C₁₅H₁₃ClN₂
Molar mass	256.73 g/mol
3D model (Jmol)	Interactive image
SMILES Clc1ccc(cc1)Cn2c3ccccc3nc2C

Chlormidazole (INN, also known as clomidazole) is used as a spasmolytic and azole antifungal drug.

Synthesis

Chlormidazole synthesis: Herrling et al., U.S. Patent 2,876,233 (1959 to Grünenthal).

Wall/
membrane

Ergosterol
inhibitors

Imidazoles	Topical: bifonazole^‡ butoconazole chlormidazole^‡ clotrimazole^# croconazole^‡ econazole fenticonazole^‡ flutrimazole isoconazole^‡ ketoconazole luliconazole miconazole^# neticonazole^‡ omoconazole^‡ oxiconazole sertaconazole sulconazole tioconazole Systemic: ketoconazole

Triazoles	Topical: efinaconazole fluconazole^# fosfluconazole terconazole Systemic: fluconazole^# hexaconazole^‡ isavuconazole itraconazole posaconazole voriconazole Unknown: albaconazole^‡ ravuconazole^†

Thiazoles	Topical: abafungin^‡

Allylamines	Topical: naftifine terbinafine Systemic: terbinafine

Benzylamines	Topical: butenafine

Others

Intracellular

Pyrimidine analogues/ thymidylate synthase inhibitors	flucytosine^#

Mitotic inhibitors	griseofulvin^#

Aminoacyl tRNA synthetase inhibitors	tavaborole

Others

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