Dimazole

Dimazole
Clinical data

ATC code	D01AE17 (WHO)
Identifiers
IUPAC name [6-(2-Diethylamino-ethoxy)-benzothiazol-2-yl]-dimethyl-amine
CAS Number	95-27-2^Y
PubChem (CID)	8708
ChemSpider	8384^N
UNII	2KL01R8ZV1^Y
ECHA InfoCard	100.002.188
Chemical and physical data
Formula	C₁₅H₂₃N₃OS
Molar mass	293.42762
3D model (Jmol)	Interactive image
Melting point	195 to 204 °C (383 to 399 °F)
SMILES CCN(CC)CCOc1ccc2c(c1)sc(n2)N(C)C
InChI InChI=1S/C15H23N3OS/c1-5-18(6-2)9-10-19-12-7-8-13-14(11-12)20-15(16-13)17(3)4/h7-8,11H,5-6,9-10H2,1-4H3^N Key:WGMYEOIMVYADRJ-UHFFFAOYSA-N^N
^NY (what is this?) (verify)

Dimazole (or diamthazole) is an antifungal.^[1]

Synthesis

Diamthazole synthesis: U.S. Patent 2,578,757

Wall/
membrane

Ergosterol
inhibitors

Imidazoles	Topical: bifonazole^‡ butoconazole chlormidazole^‡ clotrimazole^# croconazole^‡ econazole fenticonazole^‡ flutrimazole isoconazole^‡ ketoconazole luliconazole miconazole^# neticonazole^‡ omoconazole^‡ oxiconazole sertaconazole sulconazole tioconazole Systemic: ketoconazole

Triazoles	Topical: efinaconazole fluconazole^# fosfluconazole terconazole Systemic: fluconazole^# hexaconazole^‡ isavuconazole itraconazole posaconazole voriconazole Unknown: albaconazole^‡ ravuconazole^†

Thiazoles	Topical: abafungin^‡

Allylamines	Topical: naftifine terbinafine Systemic: terbinafine

Benzylamines	Topical: butenafine

Others

Intracellular

Pyrimidine analogues/ thymidylate synthase inhibitors	flucytosine^#

Mitotic inhibitors	griseofulvin^#

Aminoacyl tRNA synthetase inhibitors	tavaborole

Others

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