Clofezone

Clofezone
Combination of
Clofexamide	Antidepressant
Phenylbutazone	Non-steroidal anti-inflammatory drug
Clinical data
Trade names	Perclusone
Routes of administration	Oral, rectal, topical
ATC code	M02AA03 (WHO) M01AA05 (WHO)
Legal status
Legal status	Discontinued
Identifiers
CAS Number	17449-96-6^N
PubChem (CID)	6433695
ChemSpider	4938775^Y
UNII	5RB28NE79Y^N
^NY (what is this?) (verify)

Clofezone (trade name Perclusone) is a drug that was used to treat joint and muscular pain, but is not marketed any more. It is a combination of clofexamide, an antidepressant, and phenylbutazone, a non-steroidal anti-inflammatory drug (NSAID).^[1]^[2]

References

↑ Berger, Artur; Wachter, Helmut, eds. (1998). Hunnius Pharmazeutisches Wörterbuch (in German) (8 ed.). Walter de Gruyter Verlag. p. 343. ISBN 3-11-015793-4.
↑ Reinicke, C.; Helbing, M.; Klingenfeld, U.; Lasaroff, I.; Wessel, G. (1984). "Comparative studies on the bioavailability of various drug forms of phenylbutazone and clofezone (Perclusone)". Die Pharmazie. 39 (12): 824–827. PMID 6241720.

Non-steroidal anti-inflammatory drugs (NSAIDs) (primarily M01A and M02A, also N02BA)

Pyrazolones / Pyrazolidines	Aminophenazone Ampyrone Azapropazone Clofezone Difenamizole Famprofazone Feprazone Kebuzone Metamizole Mofebutazone Morazone Nifenazone Oxyphenbutazone Phenazone Phenylbutazone Propyphenazone Sulfinpyrazone Suxibuzone^‡

Salicylates	Aspirin (acetylsalicylic acid)^# Aloxiprin Benorylate Carbasalate calcium Diflunisal Dipyrocetyl Ethenzamide Guacetisal Magnesium salicylate Methyl salicylate Salsalate Salicin Salicylamide Salicylic acid (salicylate) Sodium salicylate

Acetic acid derivatives and related substances	Aceclofenac Acemetacin Alclofenac Amfenac Bendazac Bromfenac Bumadizone Bufexamac Diclofenac Difenpiramide Etodolac Felbinac Fenclozic acid Fentiazac Indomethacin Indomethacin farnesil Isoxepac Ketorolac Lonazolac Oxametacin Prodolic acid Proglumetacin Sulindac Tiopinac Tolmetin Zomepirac^†

Oxicams	Ampiroxicam Droxicam Isoxicam Lornoxicam Meloxicam Piroxicam Tenoxicam

Propionic acid derivatives (profens)	Alminoprofen Benoxaprofen^† Carprofen^‡ Dexibuprofen Dexketoprofen Fenbufen Fenoprofen Flunoxaprofen Flurbiprofen Ibuprofen^# Ibuproxam Indoprofen^† Ketoprofen Loxoprofen Miroprofen Naproxen Oxaprozin Pirprofen Suprofen Tarenflurbil Tepoxalin^‡ Tiaprofenic acid Vedaprofen^‡ COX-inhibiting nitric oxide donator: Naproxcinod

N-Arylanthranilic acids (fenamates)	Azapropazone Clonixin Etofenamate Flufenamic acid Flunixin Meclofenamic acid Mefenamic acid Morniflumate Niflumic acid Tolfenamic acid Flutiazin

Coxibs	Apricoxib Celecoxib Cimicoxib^‡ Deracoxib^‡ Etoricoxib Firocoxib^‡ Lumiracoxib^† Mavacoxib^‡ Parecoxib Robenacoxib^‡ Rofecoxib^† Valdecoxib^†

Other	Aminopropionitrile Benzydamine Chondroitin sulfate Diacerein Fluproquazone Glucosamine Glycosaminoglycan Hyperforin Nabumetone Nimesulide Oxaceprol Proquazone Superoxide dismutase/Orgotein Tenidap

Items listed in bold indicate initially developed compounds of specific groups. ^#WHO-EM ^†Withdrawn drugs. ^‡Veterinary use medications.

Topical products for joint and muscular pain (M02)

Anti-inflammatory
preparations,
non-steroids

Pyrazolidines	Phenylbutazone Mofebutazone Clofezone Oxyphenbutazone

Acetic acid derivatives	Tolmetin Diclofenac Fentiazac

Other	Benzydamine Etofenamate Piroxicam Felbinac Bufexamac Ketoprofen Bendazac Naproxen Ibuprofen Feprazone Niflumic acid Meclofenamic acid Flurbiprofen Suxibuzone Indometacin Nifenazone

Capsaicin derivatives

Zucapsaicin

Other

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