Danofloxacin

Danofloxacin
Clinical data

AHFS/Drugs.com	International Drug Names
ATCvet code	QJ01MA92 (WHO)
Identifiers
IUPAC name 1-Cyclopropyl-6-fluoro-7-[(1S,4S)-3-methyl-3,6-diazabicyclo[2.2.1]heptan-6-yl]-4-oxoquinoline-3-carboxylic acid
CAS Number	112398-08-0^Y
PubChem (CID)	71335
ChemSpider	64439^N
UNII	24CU1YS91D^N
ChEMBL	CHEMBL157548^N
ECHA InfoCard	100.166.385
Chemical and physical data
Formula	C₁₉H₂₀FN₃O₃
Molar mass	357.37 g/mol
3D model (Jmol)	Interactive image
SMILES O=C(O)\C4=C\N(c3cc(N1C[C@H]2N(C)C[C@@H]1C2)c(F)cc3C4=O)C5CC5
InChI InChI=1S/C19H20FN3O3/c1-21-7-12-4-11(21)8-22(12)17-6-16-13(5-15(17)20)18(24)14(19(25)26)9-23(16)10-2-3-10/h5-6,9-12H,2-4,7-8H2,1H3,(H,25,26)/t11-,12-/m0/s1^N Key:QMLVECGLEOSESV-RYUDHWBXSA-N^N
^NY (what is this?) (verify)

Danofloxacin is a fluoroquinolone antibiotic used in veterinary medicine.^[1]

References

↑ Lees, P.; Shojaee Aliabadi, F. (Apr 2002). "Rational dosing of antimicrobial drugs: animals versus humans.". Int J Antimicrob Agents. 19 (4): 269–84. doi:10.1016/s0924-8579(02)00025-0. PMID 11978498.

Antifolates
(inhibits
purine metabolism,
thereby inhibiting
DNA and RNA synthesis)

Short- acting	Sulfaisodimidine Sulfamethizole Sulfadimidine Sulfapyridine Sulfafurazole Sulfanilamide Prontosil Sulfathiazole Sulfathiourea

Intermediate- acting	Sulfamethoxazole Sulfadiazine^# Sulfamoxole

Long- acting	Sulfadimethoxine Sulfadoxine Sulfalene Sulfametomidine Sulfametoxydiazine Sulfamethoxypyridazine Sulfaperin Sulfamerazine Sulfaphenazole Sulfamazone

Other/ungrouped	Sulfacetamide Sulfadicramide Sulfametrole

Combinations

2nd g.	Ciprofloxacin^# Ofloxacin Enoxacin^‡ Fleroxacin^‡ Lomefloxacin^‡ Nadifloxacin^‡ Norfloxacin^‡ Pefloxacin^‡ Rufloxacin^‡

3rd g.	Levofloxacin Balofloxacin^‡ Grepafloxacin^‡ Pazufloxacin^‡ Sparfloxacin^‡ Temafloxacin^‡ Tosufloxacin^‡

4th g.	Besifloxacin Gatifloxacin Finafloxacin Gemifloxacin Moxifloxacin Clinafloxacin^† Garenoxacin^‡ Prulifloxacin^‡ Sitafloxacin^‡ Trovafloxacin^‡/Alatrofloxacin^‡

Vet.	Danofloxacin Difloxacin Enrofloxacin Ibafloxacin Marbofloxacin Orbifloxacin Pradofloxacin Sarafloxacin

Newer non-fluorinated

Related (DG)

Nitro- imidazole derivatives	Metronidazole^# Tinidazole Ornidazole

Nitrofuran derivatives	Nitrofurantoin^# Furazolidone^‡ Nifurtoinol

RNA synthesis

Rifamycins/ RNA polymerase	Rifampicin^# Rifabutin Rifapentine Rifaximin Rifalazil^§

This article is issued from Wikipedia - version of the 6/1/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.