Piromidic acid

Piromidic acid
Clinical data

AHFS/Drugs.com	International Drug Names
ATC code	J01MB03 (WHO)
Identifiers
IUPAC name 8-Ethyl-5-oxo-2-pyrrolidin-1-yl-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxylic acid
PubChem (CID)	4855
ChemSpider	4689
UNII	3I12WH4EWF^Y
KEGG	D01431
ECHA InfoCard	100.039.223
Chemical and physical data
Formula	C₁₄H₁₆N₄O₃
Molar mass	288.30 g/mol
3D model (Jmol)	Interactive image
SMILES CCN1C=C(C(=O)C2=CN=C(N=C21)N3CCCC3)C(=O)O
InChI InChI=1S/C14H16N4O3/c1-2-17-8-10(13(20)21)11(19)9-7-15-14(16-12(9)17)18-5-3-4-6-18/h7-8H,2-6H2,1H3,(H,20,21) Key:RCIMBBZXSXFZBV-UHFFFAOYSA-N

Piromidic acid is a quinolone antibiotic.^[1]

References

↑ Minami, Shinsaku; Shono, Toshihiro; Matsumoto, Jun-Ichi (1971). "Pyrido [2, 3-d] pyrimidine Antibacterial Agents. II. Piromidic Acid and Related Compounds". Chemical and Pharmaceutical Bulletin. 19 (7): 1426–1432. doi:10.1248/cpb.19.1426.

Antifolates
(inhibits
purine metabolism,
thereby inhibiting
DNA and RNA synthesis)

Short- acting	Sulfaisodimidine Sulfamethizole Sulfadimidine Sulfapyridine Sulfafurazole Sulfanilamide Prontosil Sulfathiazole Sulfathiourea

Intermediate- acting	Sulfamethoxazole Sulfadiazine^# Sulfamoxole

Long- acting	Sulfadimethoxine Sulfadoxine Sulfalene Sulfametomidine Sulfametoxydiazine Sulfamethoxypyridazine Sulfaperin Sulfamerazine Sulfaphenazole Sulfamazone

Other/ungrouped	Sulfacetamide Sulfadicramide Sulfametrole

Combinations

2nd g.	Ciprofloxacin^# Ofloxacin Enoxacin^‡ Fleroxacin^‡ Lomefloxacin^‡ Nadifloxacin^‡ Norfloxacin^‡ Pefloxacin^‡ Rufloxacin^‡

3rd g.	Levofloxacin Balofloxacin^‡ Grepafloxacin^‡ Pazufloxacin^‡ Sparfloxacin^‡ Temafloxacin^‡ Tosufloxacin^‡

4th g.	Besifloxacin Gatifloxacin Finafloxacin Gemifloxacin Moxifloxacin Clinafloxacin^† Garenoxacin^‡ Prulifloxacin^‡ Sitafloxacin^‡ Trovafloxacin^‡/Alatrofloxacin^‡

Vet.	Danofloxacin Difloxacin Enrofloxacin Ibafloxacin Marbofloxacin Orbifloxacin Pradofloxacin Sarafloxacin

Newer non-fluorinated

Related (DG)

Nitro- imidazole derivatives	Metronidazole^# Tinidazole Ornidazole

Nitrofuran derivatives	Nitrofurantoin^# Furazolidone^‡ Nifurtoinol

RNA synthesis

Rifamycins/ RNA polymerase	Rifampicin^# Rifabutin Rifapentine Rifaximin Rifalazil^§

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