Dacemazine
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| Clinical data | |
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| ATC code | none |
| Identifiers | |
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| CAS Number |
518-61-6  N |
| PubChem (CID) | 68846 |
| ChemSpider |
62079  Y |
| UNII |
88D34UY0QI Y |
| ChEMBL |
CHEMBL2107547 N |
| Chemical and physical data | |
| Formula | C16H16N2OS |
| Molar mass | 284.376 g/mol |
| 3D model (Jmol) | Interactive image |
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| NY (what is this?) (verify) | |
Dacemazine (INN, also known as Ahistan and Histantine)[1] is a phenothiazine derivative which acts as an histamine antagonist at the H1 subtype. First described in 1951, it was never marketed as a drug on its own, although a combination of dacemazine and di-tert-butylnaphthalenesulfonate was sold as an antispasmodic and antitussive under the trade name Codopectyl.[1] It was also assessed as a possible anticancer drug.[2]
References
- 1 2 David J. Triggle; C. R. Ganellin; F. MacDonald (1996). Dictionary of Pharmacological Agents. 1. Boca Raton: Chapman & Hall/CRC. p. 711. ISBN 0-412-46630-9. Retrieved on August 2, 2008 through Google Book Search.
- ↑ Karolyhazy G, Havas I, Jansco G, Kapas L, Sellei C. The anticarcinogenic effect of dimethylaminoacetyl-phentiazide (ahistan). Kiserletes Orvostudomany. 1952 Aug;4(4):260-2. PMID 13023855
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