Finrozole
 | |
| Names | |
|---|---|
| IUPAC name
4-[(1R,2S)-3-(4-Fluorophenyl)-2-hydroxy-1-(1,2,4-triazol-1-yl)propyl]benzonitrile | |
| Identifiers | |
| 160146-17-8 | |
| 3D model (Jmol) | Interactive image |
| ChEMBL | ChEMBL2218882 |
| ECHA InfoCard | 100.219.051 |
| PubChem | 6918277 |
| |
| |
| Properties | |
| C18H15FN4O | |
| Molar mass | 322.34 g·mol−1 |
| Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
| Infobox references | |
Finrozole is an aromatase (CYP19A1) inhibitor.[1]
References
- ↑ Huuskonen, P; Myllynen, P; Storvik, M; Pasanen, M (2013). "The effects of aflatoxin B1 on transporters and steroid metabolizing enzymes in JEG-3 cells". Toxicology letters. 218 (3): 200–6. doi:10.1016/j.toxlet.2013.01.015. PMID 23402939.
| HMGCR | |
|---|---|
| FPS | |
| 24-DHCR24 |
|
| 20,22-Desmolase (P450scc) |
|
| 17α-Hydroxylase, 17,20-Lyase |
|
| 3α-HSD | |
| 3β-HSD | |
| 11β-HSD |
|
| 21-Hydroxylase |
|
| 11β-Hydroxylase |
|
| 18-Hydroxylase |
|
| 17β-HSD |
|
| 5α-Reductase |
|
| Aromatase |
|
| SST/EST |
|
| STS |
|
| 27-Hydroxylase | |
| Others |
|
See also: Androgenics • Estrogenics • Glucocorticoidics • Mineralocorticoidics • Progestogenics | |
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